Article ID Journal Published Year Pages File Type
10800675 Biochimica et Biophysica Acta (BBA) - General Subjects 2013 12 Pages PDF
Abstract
► Recent data linking the Hippo pathway to stem cell renewal and differentiation is discussed. ► The Hippo pathway effectors TAZ and YAP control embryonic and induced pluripotent stem cell renewal. ► TAZ and YAP activity dictates mesenchymal stem cell differentiation. ► TAZ and YAP promote epithelial and neuronal progenitor proliferation. ► TAZ enhances cancer stem cell-like properties.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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