Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800675 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2013 | 12 Pages |
Abstract
⺠Recent data linking the Hippo pathway to stem cell renewal and differentiation is discussed. ⺠The Hippo pathway effectors TAZ and YAP control embryonic and induced pluripotent stem cell renewal. ⺠TAZ and YAP activity dictates mesenchymal stem cell differentiation. ⺠TAZ and YAP promote epithelial and neuronal progenitor proliferation. ⺠TAZ enhances cancer stem cell-like properties.
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Authors
Samantha E. Hiemer, Xaralabos Varelas,