Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800695 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 12 Pages |
Abstract
⺠Complex carbohydrates influence the circulatory half-life of proteins and cells. ⺠Lectin-receptors participate in clearance of glycosylated blood components. ⺠Glycosylation of transfused cold-stored platelets improves circulation time. ⺠Glycoengineering of recombinant biologics improve therapeutic effects. ⺠Understanding lectin-mediated clearance underlies biopharmaceutical progress.
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Authors
Anne Louise Tølbøll Sørensen, Henrik Clausen, Hans H. Wandall,