Article ID Journal Published Year Pages File Type
10800697 Biochimica et Biophysica Acta (BBA) - General Subjects 2012 9 Pages PDF
Abstract
► CD10 is a type II membrane glycoprotein exhibiting neutral endopeptidase activity. ► Removal of only a small part of N-glycans caused entire loss of the activity. ► CD10 lacking an N-glycan at Asn628 did not exhibit the activity. ► CD10 lacking an N-glycan at Asn628 was not expressed by the transfectants. ► An N-glycan at Asn628 is essential both for surface expression and NEP activities.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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