| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800701 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 11 Pages |
Abstract
⺠Transport of soy-derived peptides across intestinal epithelial cells was examined. ⺠The tripeptide VPY was identified as a novel substrate for the transporter PepT1. ⺠VPY reduced production of inflammatory cytokines in IECs and immune cells. ⺠VPY reduced the severity of DSS-induced colitis in mice. ⺠VPY may be a promising new therapeutic for the treatment of intestinal inflammation.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Jennifer Kovacs-Nolan, Hua Zhang, Masahisa Ibuki, Toshihiro Nakamori, Keiko Yoshiura, Patricia V. Turner, Toshiro Matsui, Yoshinori Mine,