Curcumin's pre-incubation temperature affects its inhibitory potency toward amyloid fibrillation and fibril-induced cytotoxicity of lysozyme

Article ID	Journal	Published Year	Pages	File Type
10800703	Biochimica et Biophysica Acta (BBA) - General Subjects	2012	13 Pages	PDF

Abstract

âº Fibrillogenesis of hen lysozyme is attenuated by thermally pre-treated curcumin. âº Thermally pre-treated curcumin enhances lysozyme's structural stability. âº Thermally pre-treated curcumin protects cells against fibril-induced cell death. âº Curcumin's protection toward fibril cytotoxicity relates to its thermostability.

Keywords

Amyloid Thermostability Cytotoxicity Inhibitors Pre-treatment Curcumin

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry

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Curcumin's pre-incubation temperature affects its inhibitory potency toward amyloid fibrillation and fibril-induced cytotoxicity of lysozyme

Authors

Kuan-Nan Liu, Chia-Min Lai, Yi-Ting Lee, Sung-Ning Wang, Rita P.-Y. Chen, Jeng-Shiung Jan, Hwai-Shen Liu, Steven S.-S. Wang,