Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800710 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 6 Pages |
Abstract
⺠Successful decoration of chitosan by different sialic acid analogs. ⺠Results show change in intrinsic toxicity before and after complexation of sugars. ⺠Demonstrated how unique structures effect Aβ toxicity attenuation. ⺠Results show importance of oxygen substitution and multi-OH tail of sialic acid. ⺠Results indicate oxygen containing structures will show therapeutic effectiveness.
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Authors
Dhruva Dhavale, James E. Henry,