| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800720 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 7 Pages |
Abstract
⺠The transcriptional rate of CYP21A2 is downregulated by 1α,25-dihydroxyvitamin D3. ⺠The effect is mediated by nuclear receptor VDR and comodulators VDIR and WSTF. ⺠The expression level of comodulators may shift the suppression to stimulation. ⺠This paper reports a functional VDRE in the CYP21A2 promoter. ⺠Our data indicate a novel mechanism for vitamin D action.
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Authors
Johan Lundqvist, Kjell Wikvall, Maria Norlin,