Article ID Journal Published Year Pages File Type
10800728 Biochimica et Biophysica Acta (BBA) - General Subjects 2012 8 Pages PDF
Abstract
► We show that CEppt is an effective inhibiter for α-synuclein aggregation. ► CEppt has a differential effect on the formation of soluble and insoluble aggregates. ► High molecular ratio of CEppt stabilizes oligomers. ► Drosophila model shows reduced brain aggregates and defective phenotype correction.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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Differential inhibition of α-synuclein oligomeric and fibrillar assembly in parkinson's disease model by cinnamon extract
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