| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800733 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 7 Pages |
Abstract
⺠d-Asp content of elastin increased linearly with age for normal and degenerate IVDs. ⺠Pentosidine content increased linearly for normal and degenerate IVD tissues combined. ⺠Signs of new elastin synthesis were found for degenerate IVD above 50 years. ⺠d-Asp and pentosidine may be used as markers in the aging process of IVD. ⺠IVD elastin is metabolically stable and long-lived in human disc tissues.
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Authors
Sarit-Sara Sivan, Benno Van El, Yulia Merkher, Christian E.H. Schmelzer, Anne-Marie Zuurmond, Andrea Heinz, Ellen Wachtel, Peter-Paul Varga, Aron Lazary, Marco Brayda-Bruno, Alice Maroudas,