Article ID Journal Published Year Pages File Type
10800739 Biochimica et Biophysica Acta (BBA) - General Subjects 2012 10 Pages PDF
Abstract
► Tubulin Polymerization Promoting Protein/p25 occurs in monomeric and dimeric forms. ► The binding of GTP shifts the equilibrium towards the oligomerization of the protein. ► Mathematical model was elaborated to characterize the multiple equilibrium system. ► The dimeric form has higher tubulin polymerization promoting potency. ► The dimer may play a role in the fine tuning of microtubule assembly in vivo.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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