Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800744 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 12 Pages |
Abstract
⺠Reduced AGEF-1 levels in C. elegans results in Cup and lysosomal enlargement in CC. ⺠ARL-8 functions upstream of AGEF-1 in lysosomes but downstream in uptake. ⺠AGEF-1 may function in lysosomes independent of its ARF exchange activity. ⺠ARF-1 and ARF-3 are candidate proteins as AGEF-1 substrates for the Cup defect.
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Authors
Lichun Tang, Hanna Fares, Xingfu Zhao, Wei Du, Bi-Feng Liu,