| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800760 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 9 Pages |
Abstract
⺠Cu overload induce oxidative stress in HepG2 and A-549 human-derived cells. ⺠The reaction of Cu homeostatic proteins is different in each kind of cells. ⺠Cell survival after Cu overload varied as a function of cell type. ⺠Caspase-3 and calpains are differentially activated as a function of Cu overload. ⺠Various proliferative indexes are affected by Cu uptake.
Keywords
TBARSMDACu-IUDCeruloplasminDCF-DAATCCMTSTBA3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideMTTROSThiobarbituric acidstandard deviationCell divisionOxidative stressEagle's minimum essential mediumApoptosisLungmalondialdehydeMEMMetallothioneinsAmerican Type Culture CollectionCopperCRPLiverReactive oxygen species
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Authors
Nathalie Arnal, MarÃa J. Tacconi de Alaniz, Carlos Alberto Marra,