| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800781 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 11 Pages |
Abstract
⺠AMPs exhibit cytotoxic ability by mechanism not well understood. ⺠Cell death-inducing activities by four β-hairpin AMPs were compared. ⺠At low concentration AMPs promoted cell death by different intracellular mechanisms. ⺠At high concentration AMPs promoted membrane disruption with different features. ⺠Different actions by β-hairpin AMPs are observed despite their similar structure.
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Authors
Edgar J. Paredes-Gamero, Marta N.C. Martins, Fábio A.M. Cappabianco, Jaime S. Ide, Antonio Miranda,