Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800802 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 27 Pages |
Abstract
⺠Iron has been a requirement for nearly all life from the very first organisms. ⺠We document the history of iron metabolism in health and disease. ⺠Unique and specific systems for handling iron evolved to control its catalytic nature. ⺠The plasma protein transferrin plays a key role in iron metabolism. ⺠Disturbed iron homeostasis can result in catastrophic consequences for humans.
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Authors
Alex D. Sheftel, Anne B. Mason, Prem Ponka,