| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800812 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 8 Pages |
Abstract
⺠Recent data concerning the regulation of iron homeostasis in the body by the liver is discussed. ⺠Transferrin receptor 2 plays a distinct role in the regulation of hepcidin. ⺠Transferrin receptor 2 is controlled both transcriptionally and posttranscriptionally at the level of protein stability. ⺠Transferrin receptor 2 also plays a role in erythropoiesis. ⺠The regulation of hepcidin transcription is controlled by both iron through Tf saturation and BMP6 and by inflammation.
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Authors
Juxing Chen, Caroline A. Enns,