| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10800818 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 8 Pages |
Abstract
⺠ITC is a valuable tool to characterize the thermodynamics of binding interactions. ⺠A large number of metal ions exhibit very high binding affinity to transferrin. ⺠Holo-hTf displays high affinity to TfR and favorable enthalpy and entropy changes. ⺠Both lobes of hTf appear to contribute to the thermodynamics of hTf-TfR interaction.
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Authors
Fadi Bou-Abdallah, Tyson R. Terpstra,