Article ID Journal Published Year Pages File Type
10800822 Biochimica et Biophysica Acta (BBA) - General Subjects 2012 14 Pages PDF
Abstract
► A wide variety of anions bind to apoTf. ► A few of these anions are synergistic and support the binding of iron(III). ► Conformational changes in the synergistic anion are critical for iron release. ► Competition from non-synergistic anions in vivo affects transferrin function. ► There are multiple allosteric anion binding sites that affect iron release.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
,