Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800822 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 14 Pages |
Abstract
⺠A wide variety of anions bind to apoTf. ⺠A few of these anions are synergistic and support the binding of iron(III). ⺠Conformational changes in the synergistic anion are critical for iron release. ⺠Competition from non-synergistic anions in vivo affects transferrin function. ⺠There are multiple allosteric anion binding sites that affect iron release.
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Authors
Wesley R. Harris,