Article ID Journal Published Year Pages File Type
10800827 Biochimica et Biophysica Acta (BBA) - General Subjects 2012 10 Pages PDF
Abstract
► Oligodendrocytes and choroid plexus express Tf mRNA in the brain. ► Choroid plexus secretes Tf, while Tf in oligodendrocytes is reportedly not secreted. ► Tf delivers iron to neurons but glial cells do not have mechanisms for Tf uptake. ► The amount of Tf that enters the brain through the BBB may be minimal. ► Tf in the CSF may serve as a biomarker for some neurological diseases.
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