Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800827 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2012 | 10 Pages |
Abstract
⺠Oligodendrocytes and choroid plexus express Tf mRNA in the brain. ⺠Choroid plexus secretes Tf, while Tf in oligodendrocytes is reportedly not secreted. ⺠Tf delivers iron to neurons but glial cells do not have mechanisms for Tf uptake. ⺠The amount of Tf that enters the brain through the BBB may be minimal. ⺠Tf in the CSF may serve as a biomarker for some neurological diseases.
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Authors
Dominique F. Leitner, James R. Connor,