Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800858 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2011 | 9 Pages |
Abstract
⺠Open and converging combinatorial assembly of DNA tiles was modeled. ⺠Parameters affecting time-course and distribution of end-products are predicted. ⺠We defined rules allowing estimation of model parameters from experimental data. ⺠Dependence of hybridization rates on tile structure and length is characterized. ⺠Model is expected to facilitate design of gene and combinatorial library synthesis.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Aude Laisne, Eric Lesniewska, Denis Pompon,