Article ID Journal Published Year Pages File Type
10800858 Biochimica et Biophysica Acta (BBA) - General Subjects 2011 9 Pages PDF
Abstract
► Open and converging combinatorial assembly of DNA tiles was modeled. ► Parameters affecting time-course and distribution of end-products are predicted. ► We defined rules allowing estimation of model parameters from experimental data. ► Dependence of hybridization rates on tile structure and length is characterized. ► Model is expected to facilitate design of gene and combinatorial library synthesis.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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