Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800869 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2011 | 8 Pages |
Abstract
⺠Chondroitin sulfate (CS) was isolated from the cartilage of ray fish. ⺠The structure and neurite outgrowth-promoting (NOP) activity were characterized. ⺠The NOP activity was suppressed by an anti-hepatocyte growth factor (HGF) antibody. ⺠The specific binding of HGF to the CS preparation was demonstrated. ⺠The HGF signaling seems to be involved in the NOP activity of the CS preparation.
Keywords
IdoUA2ABc-MET receptorCSaseNOPGlcUAGDNFMidkineGAGPTNHGFGalNAc2-aminobenzamideN-Acetyl-D-Galactosamined-Glucuronic acidl-Iduronic acidHepatocyte growth factorCartilageGlial cell line-derived neurotrophic factorNeurite outgrowth-promoting activityinternational unitPleiotrophinHPLChigh-performance liquid chromatographyChondroitin sulfateChondroitinaseGlycosaminoglycan
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Authors
Taishi Hashiguchi, Takanari Kobayashi, Duriya Fongmoon, Ajaya Kumar Shetty, Shuji Mizumoto, Nobuyuki Miyamoto, Toshikazu Nakamura, Shuhei Yamada, Kazuyuki Sugahara,