Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10800894 | Biochimica et Biophysica Acta (BBA) - General Subjects | 2011 | 9 Pages |
Abstract
⺠This is the first investigation of the significant photosensitizing effects of phloxine B (PhB) on human leukemia cell lines by the weak light. ⺠Our findings provide new insights into the molecular mechanisms underlying the PhB-induced apoptosis and also evaluated PhB as a promising PDT agent. ⺠We also revealed how the PhB-induced effects can be modulated by the H2O2-MPO-HOCl system to potentially compromise medicinal and therapeutic outcomes.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Hang Qi, Hiroshi Takano, Yoji Kato, Qian Wu, Chiharu Ogata, Beiwei Zhu, Yoshiyuki Murata, Yoshimasa Nakamura,