Article ID Journal Published Year Pages File Type
10800914 Biochimica et Biophysica Acta (BBA) - General Subjects 2011 6 Pages PDF
Abstract
► We establish a co-culture system to clarify the effects of vascular cells by AGEs. ► Monocytes, vein endothelial cells and aortic vascular smooth muscle cells are co-cultured. ► Proliferation of vascular smooth muscle cells (SMC) is induced by AGEs in co-culture system. ► SMC treated with AGEs express cytokines, IL-6 and MCP-1. ► Cytokines expression is elevated in the co-culture system of HUVEC and THP-1 when treated with AGEs.
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