| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10801902 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2015 | 10 Pages |
Abstract
Our results demonstrate a critical tumor suppressive role of CaSR in the colon. Restoration of CaSR expression and function is linked to regulation of the balance between proliferation, differentiation, and apoptosis and provides a rationale for novel strategies in CRC therapy.
Keywords
Calcilyticβ2MCDX2pTHMCMCaSREMPCDCCalcimimeticSCCCdt1FBSDMEMZeocinSucrase isomaltasecaudal type homeobox 2Ca2 +Dulbecco's modified Eagle's mediumBaxBeta-2-microglobulinanalysis of varianceANOVAColorectal cancerfetal bovine serumTumor suppressorSpearman correlation coefficientdominant negativewild typeparathyroid hormoneBcl-2 Associated X proteinCell division cycleCRCCalciumColonCalcium-sensing receptor
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Authors
Abhishek Aggarwal, Maximilian Prinz-Wohlgenannt, Samawansha Tennakoon, Julia Höbaus, Cedric Boudot, Romuald Mentaverri, Edward M. Brown, Sabina Baumgartner-Parzer, Enikö Kállay,