| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10801989 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2015 | 13 Pages |
Abstract
In this study we investigated the impact of RTN-1C modulation on mitochondrial dynamics. We demonstrate that RTN-1C controls mitochondrial structure and function affecting intracellular Ca2Â + homeostasis and lipid exchange between ER and mitochondria. We propose that these events depend on RTN-1C involvement in the regulation of ER-mitochondria cross-talk and define a role for RTN-1C in maintaining the function of contacts between the two organelles.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Valentina Reali, Bisan Mehdawy, Roberta Nardacci, Giuseppe Filomeni, Anna Risuglia, Federica Rossin, Manuela Antonioli, Claudia Marsella, Gian Maria Fimia, Mauro Piacentini, Federica Di Sano,