Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802012 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2015 | 20 Pages |
Abstract
This review focuses on the basic steps of Fe-S cluster biogenesis, drawing attention to recent advances achieved on the identification of molecular features that guide selection of specific subsets of nascent Fe-S recipients by the cochaperone HSC20. Additionally, it outlines the distinctive phenotypes of human diseases due to mutations in the components of the basic pathway. This article is part of a Special Issue entitled: Fe/S proteins: Analysis, structure, function, biogenesis and diseases.
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Authors
Nunziata Maio, Tracey A. Rouault,