Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802174 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2014 | 12 Pages |
Abstract
Together, these results suggest that miR-145 is a novel target of PPARγ, acts as a tumor suppressor in CRC cell lines and is a key regulator of intestinal cell differentiation by directly targeting SOX9, a marker of undifferentiated progenitors in the colonic crypts.
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Authors
Anna Panza, Carolina Votino, Annamaria Gentile, Maria Rosaria Valvano, Tommaso Colangelo, Massimo Pancione, Lucia Micale, Giuseppe Merla, Angelo Andriulli, Lina Sabatino, Manlio Vinciguerra, Clelia Prattichizzo, Gianluigi Mazzoccoli, Vittorio Colantuoni,