Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802180 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2014 | 13 Pages |
Abstract
⺠The UPS is the key player in non-lysosomal protein degradation. ⺠Natural compounds have been optimized during evolution and implement lead structure motives for drug development. ⺠The intersection of methodologies permits the discovery of novel leads. ⺠Induction of natural product biosynthesis is triggered by distinct molecular environments. ⺠The natural product family of syrbactins and their biological functions during pathogenesis
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Martin L. Stein, Michael Groll,