Article ID Journal Published Year Pages File Type
10802254 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2014 9 Pages PDF
Abstract
Shear stress enhanced the radiation toxicity to colon cancer cells through suppression of integrin signaling and protein degradation of FAK. The results of our study provide a strong rationale for cancer treatment that combines between radiation and strategy in modulating tumor interstitial fluid flow.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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Radiation sensitization of tumor cells induced by shear stress: The roles of integrins and FAK
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