Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802303 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 13 Pages |
Abstract
⺠ER stress is a condition of disturbed ER function. ⺠ER stress can lead to autophagy or apoptosis. ⺠Autophagy and apoptosis are affected by intracellular Ca2 + signaling. ⺠The activity of IP3Rs and other Ca2 +-handling proteins is modulated during ER stress. ⺠Ca2 + signals participate in cell-fate determination subsequently to ER stress.
Keywords
PDIERO1αTMBIMIICRCSQBcl-2 homology 3BH3a.a.GADD34BI-1Bcl-xLIP3RGRPeIF2αATFIRE1Bcl-2RyRPMLIP3GITMAMBiPC/EBP-homologous proteininositol 1,4,5-trisphosphateROSamino acidinositol-requiring enzyme 1CHOPendoplasmic reticulumeukaryotic initiation factor 2αmitochondria-associated membraneactivating transcription factorSERCAB-cell lymphoma 2B-cell lymphoma-extra largePromyelocytic leukemiabax inhibitor-1glucose-regulated proteinprotein disulfide isomeraseprotein kinase RNA-like ER kinasePERKCalsequestrinReactive oxygen speciesInositol 1,4,5-trisphosphate receptorRyanodine receptor
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Authors
Santeri Kiviluoto, Tim Vervliet, Hristina Ivanova, Jean-Paul Decuypere, Humbert De Smedt, Ludwig Missiaen, Geert Bultynck, Jan B. Parys,