| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802310 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 12 Pages |
Abstract
⺠Influx of Ca2 + and Na+ via TRPV1 causes cell swelling and membrane bleb formation. ⺠Elevation of [Ca2 +]i sensitizes/activates TRPV1 channels augmenting cell swelling. ⺠Calretinin expression diminishes capsaicin-induced cell volume increases. ⺠Acute capsaicin toxicity results from impaired cell membrane integrity, not apoptosis.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
László Pecze, Walter Blum, Beat Schwaller,