| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802313 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 8 Pages |
Abstract
⺠We explored functional role of the C-terminal Zn2 +-binding domain unique to S100A3. ⺠Affinity to Ca2 + and Zn2 + of S100A3 was enhanced when the other cation bound. ⺠A single Zn2 + binding accelerates Ca2 +-dependent S100A3 tetramerization. ⺠Overall shape of an S100A3 tetramer is predicted by small angle scattering analyses. ⺠Cation binding states to each S100A3 subunit propagate within a homotetramer.
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Authors
Kenji Kizawa, Yuji Jinbo, Takafumi Inoue, Hidenari Takahara, Masaki Unno, Claus W. Heizmann, Yoshinobu Izumi,