| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802317 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 11 Pages |
Abstract
⺠Bcl-2 proteins are acknowledged to be the key regulators of apoptosis. ⺠The versatile second messenger calcium can induce apoptosis by different pathways. ⺠Bcl-2 proteins regulate Ca2 + homeostasis at the ER and at the mitochondria. ⺠Beyond apoptosis, Bcl-2 proteins are involved in other cellular processes. ⺠Ca2 + homeostasis regulation may be a common mechanism for these non-apoptotic roles.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Benjamin Bonneau, Julien Prudent, Nikolay Popgeorgiev, Germain Gillet,