Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802338 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 12 Pages |
Abstract
⺠Microspherule protein Msp58 forms a novel complex with E3 ubiquitin ligase EDD. ⺠Msp58 and EDD directly interact and co-localize in the nucleoplasm. ⺠Two regions of Msp58 are sufficient to bind EDD independently. ⺠EDD negatively regulates the protein level of Msp58. ⺠The Msp58/EDD complex regulates cyclin levels and cell cycle progression.
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Authors
Mario Benavides, Lai-Fong Chow-Tsang, Jinsong Zhang, Hualin Zhong,