| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802339 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 8 Pages |
Abstract
⺠Vitamin D analog EB1089 decreases gene expression of CYP19A1 in breast cancer cells. ⺠EB1089 dissociates modulator WSTF from the CYP19A1 promoter in a VDR dependent manner. ⺠EB1089 reduces the aromatase activity. ⺠EB1089 is of interest in treatment of endocrine responsive breast cancers. ⺠WSTF is an interesting drug target for new treatments against breast cancer.
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Authors
Johan Lundqvist, Susanne Kofoed Hansen, Anne E. Lykkesfeldt,