| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802340 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 11 Pages |
Abstract
⺠NRF-2 functionally regulates critical Grin1 and Grin2b subunits of NMDA receptors. ⺠Silencing NRF-2 prevented KCl-induced up-regulation of Grin1, Grin2b, and COX. ⺠Over-expressing NRF-2 rescued TTX-induced down-regulation of Grin1, Grin2b, and COX. ⺠NRF-2 (GABP) transcriptionally coregulates energy metabolism and neuronal activity. ⺠NRF-2 and NRF-1 regulate NMDA receptors and COX in a concurrent and parallel manner.
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Authors
Anusha Priya, Kaid Johar, Margaret T.T. Wong-Riley,