Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802380 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 10 Pages |
Abstract
⺠Clear renal cell carcinoma expresses vasoactive intestinal peptide (VIP) receptors. ⺠VIP inhibited tumoral renal cell proliferation through adenylyl cyclase stimulation. ⺠Growth-inhibitory response to VIP was related to EPAC/PI3-K signaling. ⺠VIP and its agonists have a potential therapeutic role in clear renal cell cancer.
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Authors
Eva Vacas, Ana B. Fernández-MartÃnez, Ana M. Bajo, Manuel Sánchez-Chapado, Andrew V. Schally, Juan C. Prieto, MarÃa J. Carmena,