| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802382 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 11 Pages |
Abstract
⺠We examine changes in the intracellular glucose concentration in pancreatic beta-cells by a FRET based technique. ⺠We show that the FLII12Pglu-700µ-δ6 sensor and fura-2 can be used to analyze glucose and calcium at the same time. ⺠Glucose is not a pacemaker of oscillations in pancreatic beta-cells. ⺠Glucose enables intracellular calcium oscillations in pancreatic beta-cells by a KATP channel independent pathway.
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Authors
Martin Tobias Kaminski, Sigurd Lenzen, Simone Baltrusch,