Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802393 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 8 Pages |
Abstract
⺠Mitochondrial uncoupling reduces GEM effect in cancer cells ⺠GEM and UCP2 inhibition synergistically inhibit cancer cell proliferation ⺠GEM and UCP2 inhibition induce ROS-mediated apoptosis in cancer cells ⺠UCP2 expression is a potential predictive biomarker of cancer resistance to GEM ⺠UCP2 is an efficient molecular target to selectively inhibit cancer cell proliferation
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Authors
Elisa Dalla Pozza, Claudia Fiorini, Ilaria Dando, Marta Menegazzi, Anna Sgarbossa, Chiara Costanzo, Marta Palmieri, Massimo Donadelli,