Article ID Journal Published Year Pages File Type
10802393 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2012 8 Pages PDF
Abstract
► Mitochondrial uncoupling reduces GEM effect in cancer cells ► GEM and UCP2 inhibition synergistically inhibit cancer cell proliferation ► GEM and UCP2 inhibition induce ROS-mediated apoptosis in cancer cells ► UCP2 expression is a potential predictive biomarker of cancer resistance to GEM ► UCP2 is an efficient molecular target to selectively inhibit cancer cell proliferation
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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