| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802431 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 46 Pages |
Abstract
⺠p/CIP/CARM1 complex binds 204 proximal promoters in response to E2 in MCF-7 cells. ⺠Many p/CIP/CARM1 complex target genes have been implicated in cancer. ⺠20% of target genes are transcriptionally altered following 12 h E2-stimulation ⺠Jak2 is a p/CIP/CARM1 complex target gene that is transcriptionally activated by E2 ⺠Chromatin modifications at Jak2 promoter support transcriptional permissiveness
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Authors
N. Coughlan, G. Thillainadesan, J. Andrews, M. Isovic, J. Torchia,