| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802462 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 7 Pages |
Abstract
⺠LPS-stimulated NF-κB activation and inflammatory cytokine production were further increased when SR-A ligand was present. ⺠Presence of SR-A ligand further enhanced LPS-promoted the association of SR-A with TLR4. ⺠Deficiency of either SR-A or TLR4 reduced the responses of macrophages to LPS challenge. ⺠Presence of SR-A is necessary for the amplification of LPS-induced response in macrophages.
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Authors
Honghui Yu, Tuanzhu Ha, Li Liu, Xiaohui Wang, Ming Gao, Jim Kelley, Race Kao, David Williams, Chuanfu Li,