| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802465 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 8 Pages |
Abstract
⺠eIF4E is a translation factor detected in both active and inactive ribonucleoprotein complexes. ⺠Residues required for cap recognition are not required for targeting eIF4E to cytoplasmic granules. ⺠Inhibition of protein synthesis affects the localization of eIF4E mutants that does not recognize the mRNA cap. ⺠Localization in cytoplasmic granules requires a residue within eIF4E protein-protein interaction domain. ⺠The domain is different from the translation factor interaction domain.
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Authors
Paola V. Ferrero, Carla Layana, Ezequiel Paulucci, Pablo Gutiérrez, Greco Hernández, Rolando V. Rivera-Pomar,