| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802467 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 9 Pages |
Abstract
⺠Peroxisomal catalases contain non-canonical peroxisomal sorting 1 sequences (PTS1). ⺠The catalase PTS1 has reduced affinity for Pex5 relative to -SKL. ⺠The catalase PTS1 results in prolonged residence times in the cytosol. ⺠Replacing âSKI by âSKL results in reduced catalase enzyme activity in vivo. ⺠Replacing âSKI by âSKL results in accumulation of catalase aggregates in peroxisomes.
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Authors
Chris Williams, Eda Bener Aksam, Katja Gunkel, Marten Veenhuis, Ida J. van der Klei,