| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802474 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 10 Pages |
Abstract
⺠Marmorin inhibited the proliferation of breast cancer cells in vitro and in vivo. ⺠MCF7 and MDA-MB-231 cells showed differentiated sensitivity to marmorin. ⺠Marmorin down-regulates estrogen receptor α expression in MCF7 cells. ⺠MCF7 and MDA-MB-231 cells shared discrepancy of apoptotic pathways caused by marmorin.
Keywords
grp75SERMERSSERDΔΨmERαERβ17β-estradiolC/EBP homologous proteinIRE1αEndoplasmic reticulum stressCHOPApoptosisSelective estrogen receptor down-regulatorBreast cancerSelective estrogen receptor modulatorRIPMitochondrial membrane potentialRibosome inactivating proteinPERKEstrogen receptorEstrogen receptor αEstrogen receptor β
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Authors
Wen Liang Pan, Jack Ho Wong, Evandro Fei Fang, Yau Sang Chan, Xiu Juan Ye, Tzi Bun Ng,