| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802477 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 11 Pages |
Abstract
⺠SPHK1 but not SPHK2 was overexpressed in a mouse Friend erythroeukemia cell line. ⺠SPHK1 expression of Friend cells affects their proliferation and differentiation. ⺠SPHK1 expression decreased during HMBA-induced differentiation. ⺠5â²-promoter between â 53 bp and the first exon is important for SPHK1 transcription. ⺠C-MYB regulates SPHK1 transcription by its binding with the 5â²-promoter region.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
N. Mizutani, M. Kobayashi, S. Sobue, M. Ichihara, H. Ito, K. Tanaka, S. Iwaki, S. Fujii, Y. Ito, K. Tamiya-Koizumi, A. Takagi, T. Kojima, T. Naoe, M. Suzuki, M. Nakamura, Y. Banno, Y. Nozawa, T. Murate,