Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802489 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 8 Pages |
Abstract
⺠A novel approach to study nuclear protein export kinetics is described. ⺠Cells lacking the nucleoporins Nup100 or Nup2 exhibit slowed export. ⺠GLFG repeats of Nup100 are necessary for efficient protein export. ⺠FXFG repeats in Nsp1 but not Nup1 affect nuclear export kinetics. ⺠Nup mutations that affect export alter Crz1 transcription factor activity.
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Authors
Erin M. Finn, Elise P. DeRoo, George W. Clement, Sheila Rao, Sarah E. Kruse, Kate M. Kokanovich, Kenneth D. Belanger,