| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802504 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 9 Pages |
Abstract
⺠In hepatoma cell-types with low differentiation grade, miR-198 expression was prominently reduced. ⺠Central signal transducers of proliferation pathways were controlled by miR-198. ⺠miR-198 upregulates synthesis of E-cadherin and claudin-1, involved in cell adhesion and cell-cell contacts. ⺠miR-198 acts as a tumor suppressor by repression of mitogenic and motogenic activities.
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Authors
Natalia Elfimova, Elisabeth Sievers, Hannah Eischeid, Monika Kwiecinski, Andrea Noetel, Heike Hunt, Diana Becker, Peter Frommolt, Maria Quasdorff, Hans Michael Steffen, Peter Nürnberg, Reinhard Büttner, Andreas Teufel, Hans-Peter Dienes, Uta Drebber,