| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10802506 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2013 | 13 Pages |
Abstract
⺠Tagged forms of Shadoo show dual, plasma membrane and nuclear localization. ⺠The (RXXX)8 motif of Shadoo is capable of directing the protein to the nucleus. ⺠The arginines of the (RXXX)8 motif have a critical role in nuclear localization. ⺠Shadoo has a not yet identified binding partner in the nucleolus.
Keywords
YFPRPMI mediumsimian vacuolating virus 40FITC-BSASV40TTF-1NLSβ-galPrP2-deoxy-d-glucoseECLNRSPBSDMEMGFPAdenosine TriphosphateATPamino acidNucleic acid bindingβ-galactosidaseenhanced chemiluminescenceHydrophobic domainCNSRoom temperatureendoplasmatic reticulumcentral nervous systemnuclear localization signalShadooDEGshoThyroid transcription factor 1Phosphate buffered salineGPI anchorRoswell Park Memorial Institute mediumenhanced yellow fluorescent proteinenhanced green fluorescent proteinPrion proteinglycosylphosphatidylinositol anchor
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Authors
E. Tóth, P.I. Kulcsár, E. Fodor, F. Ayaydin, L. Kalmár, A.Ã. Borsy, L. László, E. Welker,