Article ID Journal Published Year Pages File Type
10802510 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 2013 9 Pages PDF
Abstract
► PTPA activated PP2A by decreasing P-PP2AC level with reduced tau phosphorylation. ► PTPA modulates the phosphorylation of PP2AC by PTP1B. ► PTPA level decreases in the brains of AD patients and transgenic mice models.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
PTPA activates protein phosphatase-2A through reducing its phosphorylation at tyrosine-307 with upregulation of protein tyrosine phosphatase 1B
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