Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802523 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 8 Pages |
Abstract
⺠Heat shock protein 90 (Hsp90) is evolutionarily conserved. ⺠Hsp90 activates and maintains numerous signaling networks in normal and cancer cells. ⺠Hsp90 chaperone function is regulated by post-translational modifications of Hsp90 and various co-chaperones. ⺠Hsp90 post-translational modifications include phosphorylation, acetylation, S-nitrosylation, oxidation, and ubiquitination.
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Authors
Mehdi Mollapour, Len Neckers,