Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10802553 | Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2012 | 7 Pages |
Abstract
⺠AAA proteases form hexameric, membrane-embedded complexes built up of homologous subunits. ⺠AAA proteases have dual activities acting as quality control and processing enzymes. ⺠AAA proteases recognize the folding state of substrate proteins. ⺠Intersubunit communication coordinates ATP hydrolysis within AAA ring and ensures maximal force generation.
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Authors
Florian Gerdes, Takashi Tatsuta, Thomas Langer,